2nd Australia-China Biomedical Research Conference

(ACBRC2009)

 

Nankai University, Tianjin, China, 24-27 April, 2009

 

Program

 

 

Friday, 24th April 2009

9:30 - 17:00

Registration  

 

 

 

13:00-17:30

Presentations from universities in Australia and China

(Room 107, Xingshen Building)

 

 

Chairperson

Prof. Wei He, Ministry of Health

 

 

13:10 - 13:40

Welcome

Prof. Zihe Rao, President, Nankai University

 

13:40 - 14:10

Prof. Gang Pei, President, Shanghai Tongji University

 

14:10 - 14:40

Prof. Tim Brown, Deputy Vice-Chancellor, La Trobe University

 

14:40 - 15:10

Prof. Qimin Zhan, Vice President, Chinese Academy of Medical Sciences/Peking Union Medical College    

 

15:10 - 15:40

Afternoon Tea

 

15:40 - 16:10

Prof. Daine Alcorn, Pro Vice Chancellor Research & Innovation, RMIT University

 

16:10 - 16:40

Prof. Baofeng Yang, President, Harbin Medical University

 

16:40 - 17:10

Prof. Linda Kristjanson, Deputy Vice-Chancellor, Curtin University of Technology

 

17:10 - 17:40

Prof. Xinan Jiao, Vice President, Yangzhou University

 

 

 

18:00 - 20:00

Welcome function (Yiyuan Restaurant, Nankai University)

 

Chairpersons

Prof. Zihe Rao, Chairman, Organizing Committee

 

 


 

 

Saturday, 25th April 2009

 

7:30 - 17:00

Registration

 

8:00 - 9:20

Opening Ceremony (Lecture Hall, Xingshen Building)

 

Chairpersons

Prof. Zihe Rao, Co-Chairman, Organizing Committee

Assoc. Prof. Jun-Ping Liu, Co-chairman, Organizing Committee

 

9:20 - 10:00

Plenary 1 (Lecture Hall, Xingshen Building)

 

Chairperson

Prof. Zihe Rao

 

09:20 - 10:00

Prof. Peter Doherty, Nobel Laureate, University of Melbourne

Progress and challenges in viral immunity

 

10:00 - 10:30

Morning Tea

 

10:30 – 12:00

Plenary 2 (Lecture Hall, Xingshen Building)

 

Chairperson

Prof. Yi Rao

 

10:30 - 11:00

Prof. John Funder, Prince Henry’s Institute of Medical Research

Translational Research Goes Both Ways: Lessons for Basic Biology from Clinical Studies

 

Chairperson

Prof. Dick Wettenhall

 

11:00 - 11:30

Prof. Heping Cheng, Peking University 

TBA

 

Chairperson

Prof. Qimin Zhan

 

11:30 - 12:00

Prof. Perry Bartlett, Queensland Brain Institute, University of Queensland

Improving learning and memory by stimulating neurogenesis in the adult brain

 

Chairperson

Prof. Ian Smith

 

12:00 - 12:30

Prof. Wei He, Chinese Academy of Medical Sciences

TBA

 

12:30 - 13:30

Lunch (Yiyuan Restaurant, Nankai University)

 

 

13:30- 17:35

Symposium 1: Stem Cell and Development

Chairpersons: Prof. Kate Loveland and Prof. Hsiao Chang Chan

(Lecture Hall, College of Life Sciences)

Symposium 2: Immunity

Chairpersons: Prof. Bryan Williams and Prof. Zhinan Yin

(Room 216, Xingshen Biulding)

13:30 - 13:55

Prof. Michael Holland, Monash Institute of Medical Research

Stem cell applications in animal biotechnology - important models for biomedical applications

Prof. Bryan Williams, Monash Institute of Medical Research

RNA interference and innate immunity

13:55 - 14:20

Prof. Hsiao Chang Chan, The Chinese University of Hong Kong

Dedifferentiated MSC-derived neurons for treatment of brain injuries

Prof. Youjia Cao, College of Life Sciences, Nankai University

New function of an old protein: the maintenance role of Vav1 in T cells

14:20 - 14:45

Prof. Paul Verma, Monash Institute of Medical Research

Approaches for generating transplantable pluripotent cells

Prof. Paul Hertzog, Monash Institute of Medical Research

Regulating pattern recognition receptor signalling in the innate immune response to infections

14:45 - 15:10

Prof. Bing Sun, Shanghai Institute of Biological Sciences

TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation

Prof. Hong Tang, Institute of Biophysics, Chinese Academy of Sciences

Adaptive immune cells temper initial innate responses

15:10 - 15:30

Afternoon Tea

15:30 - 15:55

Prof. Kate Loveland, Monash Institute of Medical Research

Cellular signalling processes that control testis development and germ line differentiation

Prof. Jennifer Stow, Institute for Molecular Bioscience, University of Queensland Brisbane

Protein trafficking and cytokine secretion in immunity

15:55 - 16:20

Lingyi Chen, College of Life Sciences, Nankai University

Cross-regulation of Nanog and Cdx2 in the segregation of the inner cell mass and the trophectoderm

Prof. Zhinan Yin, College of Life Sciences, Nankai University

γδ T cells in inflammation and cancer

16:20 - 16:45

Ying Jin, Shanghai Institute of Biological Sciences

Wwp2 Controls Oct4 Protein Levels via Lysine 63-linked Ubiquitin Chains in a Dosage-dependent Manner

Prof. Ban Hock Toh, Monash University

Pro-atherogenic activity of NKT cells resides in the CD4+ subset

16:45 - 17:10

Dr. Di Yu, Garvan Institute of Medical Research

miRNA-regulated T cell differentiation

Prof. Shunle Chen, Renji Hospital, Shanghai Jiao Tong University

Biologic agents--the new era of lupus treatment

17:10 - 17:35

Dr Rongwen Xi, National Institute of Biological Sciences

Finding the niche for Drosophila intestinal stem cells

 Profs Nan Shenn, Shanghai Jiao Tong University

Type I Interferon, Lupus Autoimmunity and Lupus Treatment

       


 

 

13:30- 17:35

Symposium 3: Cancer Progression

Chairpersons: Prof. Christine Clarke and Prof. Jinqiu Zhou

(Room 203, Xingshen Building)

Symposium 4: Cardiovascular and Neural Sciences

Chairpersons: Prof. Ian Smith and Prof. Peter Schofield

(Room 206, Xingshen Building)

13:30 - 13:55

Prof. Marc Achen, Ludwig Institute for Cancer Research

Novel therapeutic approaches for targeting blood vessels and lymphatics in cancer

Prof. Ian Smith, Monash University

New Approaches for the Discovery of Cardiovascular Disease Biomarkers

13:55 - 14:20

Prof. Jinqiu Zhou, Shanghai Institute for Biological Sciences

Sua5p Is a novel single-stranded telomeric DNA binding protein facilitating telomere replication

Prof. Baofeng Yang,   Harbin Medical University

MicroRNAs: key players in the cardiovascular system, apoptosis, arrhythmogenesis and sudden cardiac death

14:20 - 14:45

Prof. Levon Khachigian, Centre for Vascular Research, University of New South Wales

Immediate-early genes as master regulators in cancer and vascular pathobiology

Prof. Peter Little, Baker Medical Research Institute

Proteoglycan synthesis and structure as  a target for the prevention of atherosclerosis

14:45 - 15:10

Prof. Yuxin Yin, Peking University Health Science Center

p53 and PTENtwo gardians of the genome

Prof. Philip Poronnik, RMIT University

A new look at renal albumin handling

15:10 - 15:30

Afternoon Tea

15:30 - 15:55

Prof. Christine Clarke, Westmead Institute for Cancer Research

Progesterone signaling in normal and malignant breast

Prof. Peter Schofield, University of New South Wales

Genetic approaches to understanding the etiology of bipolar disorder

15:55 - 16:20

Prof. Jun Zhou, College of Life Sciences, Nankai University

Microtubule tip-associated protein EB1 promotes breast cancer growth by stimulating Aurora-B kinase activity

Prof. Yizheng Wang, Institute of Neuroscience, Shanghai Institute of Biological Sciences, Chinese Academy of Sciences

TRPCs and neuronal survival              

16:20 - 16:45

Prof. Wayne Tilley, University of Adelaide / Hanson Institute

The emerging role of androgen signaling in breast and prostate cancer

Prof. David Adams, University of Queensland

Analgesic conotoxins targeting neuronal nicotinic acetylcholine receptors or GABA-B receptors

16:45 - 17:10

Prof. Yusheng Cong, Beijing Normal University

Actions of telomerase beyond telomeres

Prof. John Rostas, University of Newcastle

Regulation of CaM-KII Activity

17:10 - 17:35

Prof. Zichun Hua, Nanjing University

TBA

Prof Shigang He, Institute of Biophysics

Development of a retinal circuit coding motion direction

 

Special event (TBA)

Chairpersons: Prof. Quan Chen and Assoc. Prof. Jun-Ping Liu

 


 

 

Sunday, 26th April 2009

 

07:30 – 17:00

Registration

 

8:30 – 10.00

Plenary 3 (Lecture Hall, Xingshen Building)

Chairpersons

Prof. Zhinan Yin

08.30 - 09.00

Prof. Tony Burgess, Ludwig Institute for Cancer Research

Colon Cancer – Stem Cell Biology, Mutations and Targeting

Chairpersons

Prof. Philip Hogg

09.00 - 09.30

Prof. Mingrong Wang, Chinese Academy of Medical Sciences

Molecular basis of the development and progression of esophageal squamous cell carcinoma

Chairpersons

Prof. Zhicheng Xiao

09.30 - 10.00

Prof. Martin Lavin, Queensland Institute of Medical Research

Role of ATM in the DNA damage response to minimise the risk of cancer and neurodegenerative disease

10.00 - 10.30

Morning Tea

10:30 – 12:00

Plenary 4 (Lecture Hall, Xingshen Building)

Chairpersons

Prof. Wayne Tilley

10.30 - 11.00

Prof. Yeguang Chen, Tsinghua University

Genome-wide Analysis of Smad Targets Reveals the Role of BMP Signaling in Embryonic Stem Cell Fate Determination

Chairpersons

Prof. Zengyi Chang

11.00 - 11.30

Prof. Peter Colman, The Walter Eliza Hall Institute of Medical Research

The influenza virus neuraminidase inhibitors

Chairpersons

Prof. Robert Saint

11.30 - 12.00

Prof. Qimin Zhan, Chinese Academy of Medical Sciences   

TBA

12.00 - 13.00

Lunch (Yiyuan Restaurant, Nankai University)

 


 

 

13:00 - 17:05

Symposium 5: Cell Biology

Chairpersons: Prof. David Huang and Prof. Pingsheng Liu

(Lecture Hall, College of Life Sciences)

Symposium 6: Cellular Signaling

Chairpersons: Prof. Peter Fuller and Prof. Heung-Chin Cheng

(Room 216, Xingshen Building)

13:00 - 13:25

Prof. Robert Saint, Australian National University

Cell division: mechanisms and consequences

Prof. Peter Fuller, Prince Henry’s Institute of Medical Research

Structural-determinants of Function in the Mineralocorticoid Receptor

13:25 - 13:50

Prof. Pingsheng Liu, Institute of Biophysics, Chinese Acadamy of Sciences

Lipid droplets: cellular lipid trafficking machinery

Prof. Mark Bartlam, College of Life Sciences, Nankai University     Structural insights into the avian influenza H5N1 virus polymerase

13:50 - 14:15

Prof. Paul Gleeson, Bio21 Molecular Science and Biotechnology Institute

Manipulation of membrane trafficking in mice using interference RNA- Inhibition of cytokine secretion

Prof. Michael Parker, St Vincent Institute of Medical Research

Structural biology of cell surface receptors

14:15 - 14:40

Prof. Baoliang Song, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences

Cholesterol Homeostasis: Sterol-regulated Protein Degradation and Trafficking

Prof. Chuanmao Zhang, College of Life Sciences, Peking University

A single amino acid change converts Aurora-A into Aurora-B-like kinase: localization, partner specificity and cellular function

14:40 - 15:00

Afternoon Tea

15:00 - 15:25

Prof. David Huang, The Walter and Eliza Hall Institute of Medical Research

Molecular control of Cell Survival

Prof. Roger Evens, Monash University

Kidney oxygen regulation: insights from combining experimental and mathematical modeling studies

15:25 - 15:50

Prof. Quan Chen, College of Life Sciences, Nankai University

Molecular regulation of mitochondrial fusion and its role in neurodegenerative diseases

Prof. Zhicheng Xiao, GSK R&D China, Shanghai

Alzheimer's Signals constrain neurogenesis

15:50 - 16:15

Prof. Rob Yang, University of New South Wales

Lipodystrophy and lipotoxicity: the role of lipid droplets

Prof. Mian Wu, University of Science and Technology

The cytosolic function of Pirh2, beyond its effect on p53 as an E3 ligase

16:15 - 16:40

Prof. Dahai Zhu, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences

Recent work on Myostatin function

Prof. Heung-Chin Cheng, University of Melbourne

Biochemical basis of differential activation of Src-family kinases Hck

and Lyn by the HIV-1 accessory protein Nef

16:40 - 17:05

Prof Stephen Jane, Royal Melbourne Hospital

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A coupling histone and DNA methylation in gene silencing

Prof. Zengyi Chang, College of Life Sciences, Peking University

Homo-oligomerization as a common way for proteins to modulate their activities

 


 

 



 

13:00 - 17:30

Symposium 7: Cancer: from genes to therapy

Chairpersons: Prof. Judith Clements and Prof. Youyong Lu

(Room 203, Xingshen Building)

Symposium 8: Metabolism and Diseases

Chairpersons: Prof. Gregory Anderson and Prof. Peng Li

(Room 206, Xingshen Building)

13:00 - 13:25

Prof. Judith Clements, Queensland University of Technology

Roles of kallikrein-related peptidases in hormone dependent cancers

Prof. Gregory Anderson, Queensland Institute of Medical Research

Regulating mammalian iron homeostasis: heavy metal in 2009

13:25 - 13:50

Prof. Ming Wei, Griffith University

Novel strategies for cancer gene therapy

Prof. Chengyu Jiang, Chinese Academy of Medical Sciences

The molecular pathogenesis of nanoparticle induced acute lung injury

13:50 - 14:15

Prof. Kum Kum Khanna, Queensland Institute of Medical Research

DNA damage response and tumorigenesis

Prof. Ian Clarke, Monash University

Targeting energy expenditure in muscle as a means of combating obesity

14:15 - 14:40

Prof. Zezhang Tao, Wuhan University School of Medicine

Effect of blocking VEGF,hTERT,Bcl-xl by multiple shRNA expression vectors on the human laryngeal squamous carcinoma

Prof. Zhanguo Li, Peking University, People's Hospital

Role of citrullinated antigens in rheumatoid arthritis  

 

14:40 - 15:00

Afternoon Tea

15:00 - 15:25

Prof. Tom Gonda, Diamantina Institute for Cancer

Establishment of high-throughput gain- and loss-of-function screening as part of a comprehensive cancer genomics facility

Prof. Dick Wettenhall, Bio21 Institute, University of Melbourne

Metabolic interactions contributing to the pathogenisis of microbial biofilm associated with periodontal disease

15:25 - 15:50

Prof. Youyong Lu, Peking University School of Oncology

Combination of miRNA and mRNA expression profiles as a classifier to predict locoregional recurrence in gastric cancer

Prof. Peng Li, Tsinghua University

Regulation of VLDL lipidation and serum lipid levels by Cideb

15:50 - 16:15

Prof. Philip Hogg, University of New South Wales

New cancer therapeutics from the study of allosteric disulfide bonds

Prof. Greg Cooney, Garvan Institute of Medical Research

Energy Balance, Obesity and Metabolic Disease

16:15 - 16:40

Prof. Qihan Dong, University of Sydney

Effect of blocking Omega-6 fatty acid releasing enzyme on cancer cell growth

 

Dr. Jiming Ye, Garvan Institute of Medical Research

Molecular mechanism of lipid-induced insulin resistance and therapeutic apoptosis

16:40 - 17:05

Prof. Mathew Vadas, Centenary Institute of Cancer Medicine and Cell Biology

Novel concepts in angiogenesis

Prof Jiake Xu., the University of Western Australia

Regulation of rab3d vesicle trafficking pathways in osteoclastic bone resorption

17:05 - 17:30

Prof. Pu Xia, Centenary Institute of Cancer Medicine and Cell Biology

Targeting sphingosine kinase-1 for cancer therapy

Dr. Louise Bennett, Biodiscovery and Separations, Food Science

Bioactive properties of dietary phytonutrients and implications for chronic disease prevention

19:00 – 21:30

Conference Dinner (Venue to be confirmed)

Chairpersons: Prof. Zihe Rao and Assoc. Prof. Jun-Ping Liu

 

Monday, 27th April 2009

07:30 – 14:00

Registration

8:30 – 10:00

Plenary 5 (Lecture Hall, Xingshen Building)

Chairpersons

Prof. Chengyu Jiang

08:30 –09:.00

Prof. Adrian Herington, Queensland University of Technology

Ghrelin gene-related peptides: multifunctional endocrine/autocrine modulators in health and disease

Chairpersons

Prof. Tom Gonda

09:00 –09:.30

Prof. Gang Pei, Shanghai Tongji University

MicroRNA-X Regulates TH17 Cell Differentiation and Pathogenesis of Multiple Sclerosis

Chairpersons

Prof. Chuanmao Zhang

09:30 – 10:00

Prof. Doug Hilton, The Walter Eliza Hall Institute of Medical Research

Genetic dissection of blood cell production

10:00 – 10:30

Morning Tea

11:00 – 12:00

Plenary 6 (Lecture Hall, Xingshen Building)

Chairpersons

Prof. Dahai Zhu

11:00 – 11:30

Prof. Andrew Roberts, Royal Melbourne Hospital

Targeting lymphoid malignancies with Bcl-2 inhibitory BH3 mimetics- translational and clinical research

Chairpersons

Prof. Roger Evans

11:30 – 12:00

Prof. Feng Shao, National Institute of Biological Sciences, Beijing

Modulation of the host innate immunity by bacterial pathogenic effectors

12:00 – 14:00

Lunch (Yiyuan Restaurant, Nankai University)

 

Conference Conclusion