2nd
(ACBRC2009)
Nankai University, Tianjin, China, 24-27 April, 2009
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Program
Friday, 24th April 2009
9:30 - 17:00
Registration
13:00-17:30
Presentations from universities in Australia and China
(Room 107, Xingshen Building)
Chairperson
Prof. Wei He, Ministry of Health
13:10 - 13:40
Welcome
Prof. Zihe Rao, President, Nankai University
13:40 - 14:10
Prof. Gang Pei, President, Shanghai Tongji University
14:10 - 14:40
Prof. Tim Brown, Deputy Vice-Chancellor, La Trobe University
14:40 - 15:10
Prof. Qimin Zhan, Vice President, Chinese Academy of Medical Sciences/Peking Union Medical College
15:10 - 15:40
Afternoon Tea
15:40 - 16:10
Prof. Daine Alcorn, Pro Vice Chancellor Research & Innovation, RMIT University
16:10 - 16:40
Prof. Baofeng Yang, President, Harbin Medical University
16:40 - 17:10
Prof. Linda Kristjanson, Deputy Vice-Chancellor, Curtin University of Technology
17:10 - 17:40
Prof. Xinan Jiao, Vice President, Yangzhou University
18:00 - 20:00
Welcome function (Yiyuan Restaurant, Nankai University)
Chairpersons
Prof. Zihe Rao, Chairman, Organizing Committee
Saturday, 25th April 2009
7:30 - 17:00
Registration
8:00 - 9:20
Opening Ceremony (Lecture Hall, Xingshen Building)
Chairpersons
Prof. Zihe Rao, Co-Chairman, Organizing Committee
Assoc. Prof. Jun-Ping Liu, Co-chairman, Organizing Committee
9:20 - 10:00
Plenary 1 (Lecture Hall, Xingshen Building)
Chairperson
Prof. Zihe Rao
09:20 - 10:00
Prof. Peter Doherty, Nobel Laureate, University of Melbourne
Progress and challenges in viral immunity
10:00 - 10:30
Morning Tea
10:30 12:00
Plenary 2 (Lecture Hall, Xingshen Building)
Chairperson
Prof. Yi Rao
10:30 - 11:00
Prof. John Funder, Prince Henrys Institute of Medical Research
Translational Research Goes Both Ways: Lessons for Basic Biology from Clinical Studies
Chairperson
Prof. Dick Wettenhall
11:00 - 11:30
Prof. Heping Cheng, Peking University
TBA
Chairperson
Prof. Qimin Zhan
11:30 - 12:00
Prof. Perry Bartlett, Queensland Brain Institute, University of Queensland
Improving learning and memory by stimulating neurogenesis in the adult brain
Chairperson
Prof. Ian Smith
12:00 - 12:30
Prof. Wei He, Chinese Academy of Medical Sciences
TBA
12:30 - 13:30
Lunch (Yiyuan Restaurant, Nankai University)
13:30- 17:35
Symposium 1: Stem Cell and Development
Chairpersons: Prof. Kate Loveland and Prof. Hsiao Chang Chan
(Lecture Hall, College of Life Sciences)
Symposium 2: Immunity
Chairpersons: Prof. Bryan Williams and Prof. Zhinan Yin
(Room 216, Xingshen Biulding)
13:30 - 13:55
Prof. Michael Holland, Monash Institute of Medical Research
Stem cell applications in animal biotechnology - important models for biomedical applications
Prof. Bryan Williams, Monash Institute of Medical Research
RNA interference and innate immunity
13:55 - 14:20
Prof. Hsiao Chang Chan, The Chinese University of Hong Kong
Prof. Youjia Cao, College of Life Sciences, Nankai University
New function of an old protein: the maintenance role of Vav1 in T cells
14:20 - 14:45
Approaches for generating transplantable pluripotent cells
Prof. Paul Hertzog, Monash Institute of Medical Research
Regulating pattern recognition receptor signalling in the innate immune response to infections
14:45 - 15:10
Prof. Bing Sun, Shanghai Institute of Biological Sciences
TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation
Prof. Hong Tang, Institute of Biophysics, Chinese Academy of Sciences
Adaptive immune cells temper initial innate responses
15:10 - 15:30
Afternoon Tea
15:30 - 15:55
Prof. Kate Loveland, Monash Institute of Medical Research
Cellular signalling processes that control testis development and germ line differentiation
Prof. Jennifer Stow, Institute for Molecular Bioscience, University of Queensland Brisbane
Protein trafficking and cytokine secretion in immunity
15:55 - 16:20
Lingyi Chen, College of Life Sciences, Nankai University
Cross-regulation of Nanog and Cdx2 in the segregation of the inner cell mass and the trophectoderm
Prof. Zhinan Yin, College of Life Sciences, Nankai University
γδ T cells in inflammation and cancer
16:20 - 16:45
Ying Jin, Shanghai Institute of Biological Sciences
Wwp2 Controls Oct4 Protein Levels via Lysine 63-linked Ubiquitin Chains in a Dosage-dependent Manner
Prof. Ban Hock Toh, Monash University
Pro-atherogenic activity of NKT cells resides in the CD4+ subset
16:45 - 17:10
Dr. Di Yu, Garvan Institute of Medical Research
miRNA-regulated T cell differentiation
Prof. Shunle Chen, Renji Hospital, Shanghai Jiao Tong University
Biologic agents--the new era of lupus treatment
17:10 - 17:35
Dr Rongwen Xi, National Institute of Biological Sciences
Finding the niche for Drosophila intestinal stem cells
Profs Nan Shenn, Shanghai Jiao Tong University
Type I Interferon, Lupus Autoimmunity and Lupus Treatment
13:30- 17:35
Symposium 3: Cancer Progression
Chairpersons: Prof. Christine Clarke and Prof. Jinqiu Zhou
(Room 203, Xingshen Building)
Symposium 4: Cardiovascular and Neural Sciences
Chairpersons: Prof. Ian Smith and Prof. Peter Schofield
(Room 206, Xingshen Building)
13:30 - 13:55
Prof. Marc Achen, Ludwig Institute for Cancer Research
Novel therapeutic approaches for targeting blood vessels and lymphatics in cancer
Prof. Ian Smith, Monash University
New Approaches for the Discovery of Cardiovascular Disease Biomarkers
13:55 - 14:20
Prof. Jinqiu Zhou, Shanghai Institute for Biological Sciences
Sua5p Is a novel single-stranded telomeric DNA binding protein facilitating telomere replication
Prof. Baofeng Yang, Harbin Medical University
MicroRNAs: key players in the cardiovascular system, apoptosis, arrhythmogenesis and sudden cardiac death
14:20 - 14:45
Prof. Peter Little, Baker Medical Research Institute
Proteoglycan synthesis and structure as a target for the prevention of atherosclerosis
14:45 - 15:10
Prof. Yuxin Yin, Peking University Health Science Center
Prof. Philip Poronnik, RMIT University
A new look at renal albumin handling
15:10 - 15:30
Afternoon Tea
15:30 - 15:55
Prof. Christine Clarke, Westmead Institute for Cancer Research
Progesterone signaling in normal and malignant breast
Prof. Peter Schofield, University of New South Wales
Genetic approaches to understanding the etiology of bipolar disorder
15:55 - 16:20
Prof. Jun Zhou, College of Life Sciences, Nankai University
Microtubule tip-associated protein EB1 promotes breast cancer growth by stimulating Aurora-B kinase activity
Prof. Yizheng Wang, Institute of Neuroscience, Shanghai Institute of Biological Sciences, Chinese Academy of Sciences
TRPCs and neuronal survival
16:20 - 16:45
Prof. Wayne Tilley, University of Adelaide / Hanson Institute
The emerging role of androgen signaling in breast and prostate cancer
Prof. David Adams, University of Queensland
Analgesic conotoxins targeting neuronal nicotinic acetylcholine receptors or GABA-B receptors
16:45 - 17:10
Prof. Yusheng Cong, Beijing Normal University
Actions of telomerase beyond telomeres
Prof. John Rostas, University of Newcastle
Regulation of CaM-KII Activity
17:10 - 17:35
Prof. Zichun Hua, Nanjing University
TBA
Prof Shigang He, Institute of Biophysics
Development of a retinal circuit coding motion direction
Special event (TBA)
Chairpersons: Prof. Quan Chen and Assoc. Prof. Jun-Ping Liu
Sunday, 26th April 2009
07:30 17:00
Registration
8:30 10.00
Plenary 3 (Lecture Hall, Xingshen Building)
Chairpersons
Prof. Zhinan Yin
08.30 - 09.00
Prof. Tony Burgess, Ludwig Institute for Cancer Research
Colon Cancer Stem Cell Biology, Mutations and Targeting
Chairpersons
Prof. Philip Hogg
09.00 - 09.30
Prof. Mingrong Wang, Chinese Academy of Medical Sciences
Molecular basis of the development and progression of esophageal squamous cell carcinoma
Chairpersons
Prof. Zhicheng Xiao
09.30 - 10.00
Prof. Martin Lavin, Queensland Institute of Medical Research
Role of ATM in the DNA damage response to minimise the risk of cancer and neurodegenerative disease
10.00 - 10.30
Morning Tea
10:30 12:00
Plenary 4 (Lecture Hall, Xingshen Building)
Chairpersons
Prof. Wayne Tilley
10.30 - 11.00
Prof. Yeguang Chen, Tsinghua University
Genome-wide Analysis of Smad Targets Reveals the Role of BMP Signaling in Embryonic Stem Cell Fate Determination
Chairpersons
Prof. Zengyi Chang
11.00 - 11.30
Prof. Peter Colman, The Walter Eliza Hall Institute of Medical Research
The influenza virus neuraminidase inhibitors
Chairpersons
Prof. Robert Saint
11.30 - 12.00
Prof. Qimin Zhan, Chinese Academy of Medical Sciences
TBA
12.00 - 13.00
Lunch (Yiyuan Restaurant, Nankai University)
13:00 - 17:05
Symposium 5: Cell Biology
Chairpersons: Prof. David Huang and Prof. Pingsheng Liu
(Lecture Hall, College of Life Sciences)
Symposium 6: Cellular Signaling
Chairpersons: Prof. Peter Fuller and Prof. Heung-Chin Cheng
(Room 216, Xingshen Building)
13:00 - 13:25
Prof. Robert Saint, Australian National University
Cell division: mechanisms and consequences
Prof. Peter Fuller, Prince Henrys Institute of Medical Research
Structural-determinants of Function in the Mineralocorticoid Receptor
13:25 - 13:50
Prof. Pingsheng Liu, Institute of Biophysics, Chinese Acadamy of Sciences
Lipid droplets: cellular lipid trafficking machinery
Prof. Mark Bartlam, College of Life Sciences, Nankai University Structural insights into the avian influenza H5N1 virus polymerase
13:50 - 14:15
Prof. Paul Gleeson, Bio21 Molecular Science and Biotechnology Institute
Manipulation of membrane trafficking in mice using interference RNA- Inhibition of cytokine secretion
Prof. Michael Parker, St Vincent Institute of Medical Research
Structural biology of cell surface receptors
14:15 - 14:40
Prof. Baoliang Song, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
Cholesterol Homeostasis: Sterol-regulated Protein Degradation and Trafficking
Prof. Chuanmao Zhang, College of Life Sciences, Peking University
A single amino acid change converts Aurora-A into Aurora-B-like kinase: localization, partner specificity and cellular function
14:40 - 15:00
Afternoon Tea
15:00 - 15:25
Molecular control of Cell Survival
Prof. Roger Evens, Monash University
Kidney oxygen regulation: insights from combining experimental and mathematical modeling studies
15:25 - 15:50
Prof. Quan Chen, College of Life Sciences, Nankai University
Molecular regulation of mitochondrial fusion and its role in neurodegenerative diseases
Prof. Zhicheng Xiao, GSK R&D China, Shanghai
Alzheimer's Signals constrain neurogenesis
15:50 - 16:15
Prof. Rob Yang, University of New South Wales
Lipodystrophy and lipotoxicity: the role of lipid droplets
Prof. Mian Wu, University of Science and Technology
The cytosolic function of Pirh2, beyond its effect on p53 as an E3 ligase
16:15 - 16:40
Prof. Dahai Zhu, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences
Recent work on Myostatin function
Prof. Heung-Chin Cheng, University of Melbourne
Biochemical basis of differential activation of Src-family kinases Hck
and Lyn by the HIV-1 accessory protein Nef
16:40 - 17:05
Prof Stephen Jane, Royal Melbourne Hospital
PRMT5-mediated methylation of histone H4R3 recruits DNMT3A coupling histone and DNA methylation in gene silencing
Prof. Zengyi Chang, College of Life Sciences, Peking University
Homo-oligomerization as a common way for proteins to modulate their activities
13:00 - 17:30
Symposium 7: Cancer: from genes to therapy
Chairpersons: Prof. Judith Clements and Prof. Youyong Lu
(Room 203, Xingshen Building)
Symposium 8: Metabolism and Diseases
Chairpersons: Prof. Gregory Anderson and Prof. Peng Li
(Room 206, Xingshen Building)
13:00 - 13:25
Prof. Gregory Anderson, Queensland Institute of Medical Research
Regulating mammalian iron homeostasis: heavy metal in 2009
13:25 - 13:50
Prof. Ming Wei, Griffith University
Novel strategies for cancer gene therapy
Prof. Chengyu Jiang, Chinese Academy of Medical Sciences
The molecular pathogenesis of nanoparticle induced acute lung injury
13:50 - 14:15
Prof. Ian Clarke, Monash University
Targeting energy expenditure in muscle as a means of combating obesity
14:15 - 14:40
Prof. Zezhang Tao, Wuhan University School of Medicine
Prof. Zhanguo Li, Peking University, People's Hospital
Role of citrullinated antigens in rheumatoid arthritis
14:40 - 15:00
Afternoon Tea
15:00 - 15:25
Prof. Tom Gonda, Diamantina Institute for Cancer
Establishment of high-throughput gain- and loss-of-function screening as part of a comprehensive cancer genomics facility
Prof. Dick Wettenhall, Bio21 Institute, University of Melbourne
Metabolic interactions contributing to the pathogenisis of microbial biofilm associated with periodontal disease
15:25 - 15:50
Prof. Youyong Lu, Peking University School of Oncology
Combination of miRNA and mRNA expression profiles as a classifier to predict locoregional recurrence in gastric cancer
Prof. Peng Li, Tsinghua University
Regulation of VLDL lipidation and serum lipid levels by Cideb
15:50 - 16:15
Prof. Philip Hogg, University of New South Wales
New cancer therapeutics from the study of allosteric disulfide bonds
Prof. Greg Cooney, Garvan Institute of Medical Research
Energy Balance, Obesity and Metabolic Disease
16:15 - 16:40
Prof. Qihan Dong, University of Sydney
Effect of blocking Omega-6 fatty acid releasing enzyme on cancer cell growth
Dr. Jiming Ye, Garvan Institute of Medical Research
Molecular mechanism of lipid-induced insulin resistance and therapeutic apoptosis
16:40 - 17:05
Prof. Mathew Vadas, Centenary Institute of Cancer Medicine and Cell Biology
Novel concepts in angiogenesis
Prof Jiake Xu., the University of Western Australia
Regulation of rab3d vesicle trafficking pathways in osteoclastic bone resorption
17:05 - 17:30
Prof. Pu Xia, Centenary Institute of Cancer Medicine and Cell Biology
Targeting sphingosine kinase-1 for cancer therapy
Dr. Louise Bennett, Biodiscovery and Separations, Food Science
Bioactive properties of dietary phytonutrients and implications for chronic disease prevention
19:00 21:30
Conference Dinner (Venue to be confirmed)
Chairpersons: Prof. Zihe Rao and Assoc. Prof. Jun-Ping Liu
Monday, 27th April 2009
07:30 14:00
Registration
8:30 10:00
Plenary 5 (Lecture Hall, Xingshen Building)
Chairpersons
Prof. Chengyu Jiang
08:30 09:.00
Prof. Adrian Herington, Queensland University of Technology
Ghrelin gene-related peptides: multifunctional endocrine/autocrine modulators in health and disease
Chairpersons
Prof. Tom Gonda
09:00 09:.30
Prof. Gang Pei, Shanghai Tongji University
MicroRNA-X Regulates TH17 Cell Differentiation and Pathogenesis of Multiple Sclerosis
Chairpersons
Prof. Chuanmao Zhang
09:30 10:00
Prof. Doug Hilton, The Walter Eliza Hall Institute of Medical Research
Genetic dissection of blood cell production
10:00 10:30
Morning Tea
11:00 12:00
Plenary 6 (Lecture Hall, Xingshen Building)
Chairpersons
Prof. Dahai Zhu
11:00 11:30
Prof. Andrew Roberts, Royal Melbourne Hospital
Targeting lymphoid malignancies with Bcl-2 inhibitory BH3 mimetics- translational and clinical research
Chairpersons
Prof. Roger Evans
11:30 12:00
Prof. Feng Shao, National Institute of Biological Sciences, Beijing
Modulation of the host innate immunity by bacterial pathogenic effectors
12:00 14:00
Lunch (Yiyuan Restaurant, Nankai University)
Conference Conclusion