Inaugural Australia-China Biomedical Research Conference

(ACBRC2007)

Walter and Eliza Hall Institute of Medical Research

Melbourne, 1-3 February 2007

Conference Program

 

1st Australia – China Biomedical Research Conference

“From Molecules & Cells to Diseases”

 

Thursday, 1st February 2007
12.00 - 17.00	Registration: Travel Inn Hotel and Elizabeth Tower Hotel
14.30 - 17.00	Melbourne City Tour
17.30 - 20.00	Welcome function (Government House)
18.00 - 18.15	Professor David de Kretser, Governor of Victoria Hon. John Brumby MP, Minister for Innovation, Government of Victoria Mr Shugen Liang, Consul-General, Chinese Consulate in Melbourne Associate Professor Jun-Ping Liu, Chair, Organising Committee
Friday, 2nd February 2007, Walter and  Eliza Hall Institute of Medical Research
7:30 – 2.00 am	Registration
8:25 – 9.20 am	Opening Ceremony (Lecture Theatre)
Chairperson	A/Prof. Jun-Ping Liu, President of ACABS
08.25 - 08.30	A/Prof. Jun-Ping Liu, President of ACABS
08.30 - 08.40	Prof. David de Kretser, Governor of Victoria
08.40 - 08.50	Mr. Shugen Liang, Consul General, Chinese Consulate in Melbourne
08.50 - 09.00	Prof. Warwick Anderson, CEO, NHMRC
09.00 - 09.10	Prof. Richard Larkins, President, Monash University
09.10 - 09.20	Prof. Suzanne Cory, Director, Walter and  Eliza Hall Institute of Medical Research
9:20 – 10:00 am	Plenary 1 (Lecture Theatre)
Chairperson	Prof. Michael Berndt, Monash University
09.20 - 10.00	Prof. Peter Doherty, Nobel Laureate Plagues, pestilences and influenza
10.00 - 10.30	Morning Tea
10:30 – 12:00 pm	Plenary 2 (Lecture Theatre)
Chairperson	Prof. Dick Wettenhall, University of Melbourne
10.30 - 11.00	Prof. Zihe Rao, Nankai University Structural proteomics of the SARS coronavirus: insights into the replication machinery
Chairperson	Prof. Ban Hock Toh, Monash University
11.00 - 11.30	Prof. Tony Burgess, Ludwig Institute for Cancer Research Colon cancer : Biochemistry and Biology
Chairperson	Prof. Martin Lavin, Queensland Institute of Medical Research
11.30 - 12.00	Prof. Weifeng Chen, Peking University Health Science Center Identification of novel human tumor-associated antigens in hepatocellular carcinoma and their potentials in clinical application
12.00 - 12.45	Lunch
12.45 – 13.10 pm	Travel Award Presentation (Lecture Theatre)
Chairpersons	A/Prof. Jun-Ping Liu and A/Prof. Chen Chen
12.45 - 13.10	Young Investigator Travel Award Presentation Presenters: Prof David de Kretser, Prof Richard Larkins, Prof Suzanne Cory, Prof Jane Gilmour, Prof Dick Wettenhall
13.00 - 13.10	Prof. Richard Larkins, President, Monash University
13.10 – 14.40 pm	Plenary 3 (Lecture Theatre)
Chairpersons	Prof. Mike Calford, University of Newcastle
13.10 - 13.40	Prof. Colin Masters, Laureate Professor, University of Melbourne Alzheimer’s disease: Aβ-amyloid as the molecular therapeutic and diagnostic target
Chairpersons	Prof. Paul Gleeson, University of Melbourne
13.40 - 14.10	Prof. Gang Pei, Shanghai Institutes of Biological Sciences Regulation of Brain Functions by G-Protein Coupled Receptor Signaling: More and Tighter than We Thought?
Chairpersons	Prof. Levon Khachigian, University of New South Wales
14.10 – 14.40	Prof. Evan Simpson, Prince Henry’s Institute of Medical Research Oestrogens - the good, the bad, and the unexpected
14.40 – 15.00	Afternoon Tea
15.00 – 17.45 pm	Symposium 1: Stem Cell Biology (Seminar Room)
Chairpersons	Dr. Fangxu Jiang, Western Australian Institute for Medical Research Prof. Richard Boyd, Monash University
15.00 - 15.20	Dr. Lorraine Robb, Walter Eliza Hall Institute of Medical Research Endodermal patterning during murine embryogenesis
15.20 - 15.40	Prof. Hsiao Chang Chan, The Chinese University of Hong Kong From epithelial cells to body function and disease
15.40 - 16.00	Prof. Richard Boyd, Monash Immunology and Stem cell Laboratories Manipulation of the immune system to improve HSCT and develop transplantation tolerance for stem cell therapies
16.00 - 16.20	A/Prof Ming Li, The Chinese University of Hong Kong Repair of infarcted heart by increasing cardiogenic differentiation efficiency of stem cells by Chinese herb
16.20 - 16.40	A/Prof Geoffrey Lindeman, The Walter Eliza Hall Institute of Medical Research Mammary stem cells and breast cancer
16.40 - 17.00	A/Prof. Xin-fu Zhou, Flinders University Neural stem cells from the peripheral nervous system and the significance
17.00 - 17.15	Mr. Mao Chen, Sichuan University Stem Cells Transplantation Results in Abnormalities of Ventricular Electrophysiology in Doxorubicin-induced Heart Failure
17.15 - 17.30	Mr. Qilai Huang, Nanjing University Application to immunoassays of the fusion protein between protein ZZ and enhanced green fluorescent protein
17.30 - 17.45	Dr. Xiaoyun Wang, The Hong Kong Polytechnic University The effect of low intensity pulsed ultrasound on osteogenesis in spinal fusion with rhBMP-4 incorporated collagen hydrogel graft
15.00 – 17.45 pm	Symposium 2: Molecular Basis of Cancer (Lecture Theatre)
Chairpersons	Dr. Hongjian Zhu, University of Melbourne Prof. Andrew Roberts, The Walter Eliza Hall Institute of Medical Research
15.00 - 15.20	Prof. Qinghua Shi, University of Science and Technology of China A Pathway of Generation of Aneuploid Cells
15.20 - 15.40	Prof. Steven Stacker, Ludwig Institute for Cancer Research Molecular pathways for lymphangiogenesis and their role in human disease
15.40 - 16.00	Prof. Jianguo Song, Shanghai Institute of Biological Sciences Regulation of transforming growth factor-1–induced apoptosis and epithelial-to-mesenchymal transition by protein kinase A and signal transducers and activators of transcription 3
16.00 - 16.20	Dr. Xiaoping Chen, Beijing Astronaut Research Centre Role of Smad3 in weightlessness-induced muscle atrophy
16.20 - 16.40	Prof. Andrew Roberts, Walter and  Eliza Hall Institute of Medical Research Targeting Bcl-2 and Bcl‑xL with BH3 mimetics – a new therapeutic approach for lymphoid malignancies providing unexpected insights to platelet physiology
16.40 - 17.00	Prof. Mian Wu, University of Science and Technology of China Phosphorylation of Pirh2 by Calmodulin-dependent kinase II leads to an increase in p53 stability
17.00 - 17.15	Mr. Yupeng Chen, Peking University Health Science Center Mechanistic Role of HMG Box Protein SOX2 in Breast Carcinogenesis
17.15 - 17.30	Ms. Rongxia Li, Shanghai Institutes of Biological Sciences Comparison of Proteomic Approach to Microarray-based Approach for Detecting Exons of Mouse Genome
17.30 - 17.45	Ms. Yingying Jia, Shanghai Institutes of Biological Sciences Thymine DNA Glycosylase potentiates transactivation of b-catenin-LEF-1 complex
16:00 – 18:00	Special Forum: Building Commercial Linkages with China
Chairpersons	Mr. Tim Murphy, Executive Director, BioMelbourne Network Mr. Geoff Lawler,   Director – Sustainability, City of Melbourne
16.00 - 17.10	Dr. John Raff, Chairman, BioMelbourne Network Prof. Zihe Rao, President, Tianjin International Joint Academy of Biotechnology and Medicine (TJAB) Dr. Jonathan Coates, CSO, Avexa Prof Gang Pei, President, Shanghai Institutes of Biological Sciences Dr. Lisa Nelson, General Manager, Nucleus Network Dr. Wei-Dong Xie, CK Life Sciences, Hong Kong
17.10 - 17.50	Panel Discussion
17.50 - 18.00	Conclusion by Mr Tim Murphy
18:00 – 19:30 pm	City of Melbourne Reception: Cocktail Party
Chairpersons	Mr. Edgar Dong, City of Melbourne Dr. Ruchong Ou, Baker Medical Research Institute
Saturday, 3rd February 2007
07.30 - 14.00	Registration
8:30 – 10.00 am	Plenary 4 (Lecture Theatre)
Chairpersons	Prof. Rob Parton, University of Queensland
08.30 - 09.00	Prof. Dick Wettenhall, Director, Bio21 Institute Recent advances in mass spectrometry- and NMR-based proteomic and metabolomic investigations of biomarkers of cellular regulation and disease
Chairpersons	Prof. Christina Mitchell, Monash University
09.00 - 09.30	Prof. Martin Lavin, Queensland Institute of Medical Research DNA Damage Response: A Barrier to Malignancy and Neurodegeneration
Chairpersons	Prof. David Adams, Queensland University
09.30 - 10.00	Prof. Levon Khachigian, University of New South Wales Roles of Immediate-Early Genes In angiogenesis, Vscular Prmeability and Inflammation: Novel Insights Using Catalytic DNA
10.00 - 10.30	Morning tea
10:30 – 12.45 am	Symposium 3: Cell Signaling and Function (Seminar Room)
Chairpersons	A/Prof. Chen Chen, Prince Henry’s Institute of Medical Research Dr. Xiao-Jun Du, Baker Heart Research Institute
10.30 - 10.50	Prof. David Adams, Queensland University Dissecting Pain Pathways with Conotoxins
10.50 - 11.10	Prof. Po Sing Leung, The Chinese University of Hong Kong Protective Mechanisms for The Renin-Angiotensin System Blockade: Novel Roles of The Pancreatic islet Angiotensin System in Diabetes
11.10 - 11.30	A/Prof Heung-Chin Cheng, University of Melbourne C-Terminal Src Kinase-Homologous Kinase (CHK) – A Unique Endogenous Inhibitor Suppressing All Active Forms of Src-family Tyrosine Kinases
11.30 - 11.50	A/Prof. Pu Xia, Adelaide University Sphingosine kinase-1, a unique signalling enzyme, serves as an ideal anti-cancer drug target
11.50 - 12.10	Prof. Wei-Jin Zang, Xian Jiaotong University Protective effects of acetylcholine and adenosine on contractility of isolated rat ventricular myocytes and arterial endothelial dysfunction
12.10 - 12.30	Professor Hong-yang Wang, Eastern Hepatobiliary Surgery Hospital Negative Regulation of Oncogenic Signaling by Signal Regulatory Protein -1
12.30 - 12.45	Ms. Connie Chu, Prince Henry’s Institute of Medical Research Regulation of transmembrane ion channel activities by angiotensin II in primary cultured mouse pancreatic beta-cells under normal and elevated glucose conditions
10:30 – 12.45 am	Symposium 4: Immunity and Disease (1) (Lecture Theatre)
Chairpersons	Dr. Li Wu, The Walter Eliza Hall Institute of Medical Research Prof. Ban Hock Toh, Monash University
10.30 - 10.50	Prof. Paul Hertzog, Monash Institute of Medical Research The role of interferons in regulating innate immune responses by toll-like receptors
10.50 - 11.10	Prof. Shunle Chen, Shanghai Jiaotong University An Update on Novel Targeted Therapies for Systemic Lupus Erythematosus
11.10 - 11.30	Prof. Zi-chun Hua, Nanjing University FAK expression: regulation and therapeutic potential
11.30 - 11.50	Prof. Feng Shao, National Institute of Biological Science, Beijing A Pathogenic Effector Family Functions as a MAPK Phosphothreonine Lyase to Inhibit MAPK Signaling Pathways
11.50 - 12.10	Dr. Li Wu, The Walter Eliza Hall Institute of Medical Research Distinct Functional Capacities of Mouse Dendritic Cell Populations
12.10 - 12.30	Prof. Zhan-guo Li, Peking University Health Science Center Inhibitory effects of altered collagen II peptide ligands in rheumatoid arthritis patients and collagen-induced arthritis
12.30 - 12.45	Ms. Li Wang, Wuhan University Combining targeted-microbubbles with low-frequency ultrasound for ischemic stroke treatment
10:30 – 12.45 am	Symposium 5: Cell Biology (Board Room)
Chairpersons	A/Prof. Jun-Ping Liu, Monash University Prof. Martin Lavin, Queensland Institute of Medical Research
10.30 - 10.50	Prof. Robert Parton, University of Queensland Caveolae and Caveolins; Linking Signal Transduction and Lipid Regulation
10.50 - 11.10	Prof. Pingsheng Liu, Guizhou University Regulation of Neutral Lipid Retention by Rab GTPases and Mono-ADP-Ribosylation of CtBP1/BARS
11.10 - 11.30	Prof. Paul Gleeson, University of Melbourne Probing the role of a family of trans-Golgi network golgins in membrane trafficking by RNA interference
11.30 - 11.50	Prof. Xueliang Zhu, Shanghai Institutes of Biological Sciences Regulation of cytoplamsic dynein functions in mitosis
11.50 - 12.10	Prof. Christina Mitchell, Monash University Regulation of PtdIns(3,4,5)P3 at the macrophage phagocytic cup by inositol polyphosphate 5-phosphatases
12.10 - 12.30	Prof. Jiarui Wu, Shanghai Institutes of Biological Sciences Comparison of Proteomic Approach to Microarray-based Approach for Detecting Exons of Mouse Genome
12.30 - 12.45	Ms. Lan Wang, Peking University Health Science Center ACDF1, autophagic cell death factor 1, regulates cell autophagy and apoptosis
12.45 – 13.30	Lunch
13.30 – 15.30 pm	Symposium 6: Immunity and Disease (2) (Lecture Theatre)
Chairpersons	A/Prof. Weisan Chen, Ludwig Institute for Cancer Research Prof. Peter Doherty, University of Melbourne
13.30 - 13.50	A/Prof. Weisan Chen, Ludwig Institute for Cancer Research Immunoproteasome subunit deficiencies impact differentially upon two immunodominant influenza virus specific CD8+ T cell responses
13.50 - 14.10	Prof. Wenling Han, Peking University Health Science Center Molecule cloning and functional study of CMTM family
14.10 - 14.30	A/Prof. Cory J Xian, University of Adelaide Mechanisms for methotrexate chemotherapy-induced bone growth defects and protective effects of folinic acid supplementary treatment
14.30 - 14.50	Prof. Xuejun Zhang, Shanghai Institutes of Biological Sciences The CCAAT-binding Factor CBF/NF-Y regulates the human acetylcholinesterase promoter activity during calcium ionophore A23187-induced cell apoptosis
14.50 - 15.10	Prof. Yu Zhang, Peking University Health Science Center Human TFDP3, a Novel DP protein, Inhibits DNA Binding and Transactivation by E2F
15.10 - 15.30	Prof Nan Shen, Shanghai Jiaotong University of Medical College Delineating novel genetic pathways of human lupus
13.30 – 15.30 pm	Symposium 7: Neuroscience (Board Room)
Chairpersons	A/Prof. Chen Chen, Prince Henry’s Institute of Medical Research Prof. Xiaomin Wang, Capital Medical University
13.30 – 13.50	Prof. Mike Calford, University of Newcastle Locally synthesized steroids control inhibitory gain in the mammalian brain
13.50 - 14.10	Prof. Kewei Wang, Peking University Health Science Center Structural Basis for Modulation of Kv4 K+ Channels by Auxiliary KCHIP Subunits
14.10 - 14.30	Prof. Peter Dunkley, University of Newcastle PACAP stimulates the sustained phosphorylation of tyrosine hydroxylase at serine 40
14.30 – 14.50	Prof. Xiaobing Yuan, Shanghai Institute of Biological Sciences Semaphorin-3A Guides the Radial Migration of Cortical Neurons during Development
14.50 - 15.10	Prof. Xiaomin Wang, Capital Medical University Chinese Herb Tripterygium Wilfordii Hook F Monomers
15.10 - 15.20	Ms. Bing Xue, Peking University Health Science Center Triptolide Upregulates NGF Synthesis in Rat Astrocyte Cultures
15.20 - 15.30	Ms. Ying Tang, Harbin Medical University The effects of selective mild hypothermia on neuronal injury and expression of astrocytic proteins following selective cerebral ischemia in rats
13.30 – 15.30 pm	Symposium 8: Tumor Targeting (Seminar Room)
Chairpersons	Dr. Hongjian Zhu, University of Melbourne Prof. Joanne Chung, The Hong Kong Polytechnic University
13.30 - 13.50	Prof. Bryan Williams, Monash Institute of Medical Research Cellular responses to double-stranded RNA: Distinguishing self from non-self
13.50 - 14.10	Prof. Ding-Gan Liu, Shanghai Institutes of Biological Sciences C/EBPb: A Possible Candidate Gene for Cancer Gene Therapy
14.10 - 14.30	Dr. David Huang, The Walter Eliza Hall Institute of Medical Research The Bcl-xL:Bak axis controls platelet survival: programmed anuclear cell death restricts platelet life span
14.30 - 14.50	Prof. Quan Chen, Beijing Institute of Zoology Drug induced apoptosis and drug discovery
14.50 - 15.05	Mr. Yuanfeng Liu, Peking University Health Science Center A Novel Pyrophosphohydrolase Cloned From Thymus and its Impact on Thymopoiesis
15.05 - 15.20	Ms. Jing Jia, Sichuan University Prevention of murine experimental autoimmune encephalomyelitis by an immunotoxin IL-18-DT390